The Role of Oxidative Stress in the Occurrence of Neurological Diseases and Cancer

The human body needs both types of oxidants (free radicals) and antioxidants for normal metabolism, signal transduction, and order of cellular activities. Free radicals can be useful (necessary) or harmful (toxic) for the body. They have a dual role. The human body has an antioxidant mechanism to fight free radicals. A balance between free radicals and antioxidants is necessary for the physiological functioning of the body. Disturbance of the balance between the production of free radicals and antioxidants is called oxidative stress. This article is a review. Therefore, materials related to the subject were collected and studied using reliable scientific sources. Oxidative stress can change cell membranes and important cell structures such as proteins, lipids, deoxyribonucleotides (DNA), and carbohydrates. Oxidative stress is one of the effective factors in many diseases. In this article, an overview of the damage caused to the body by oxidative stress and its relationship bWe deal with human diseases such as stroke, diabetic nephropathy, Parkinson's, Huntington's, Alzheimer's, autism, cancer, and other phenomena such as aging.