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Context: Latest global cancer data confirmed that there are 18.1 million new cancer cases and 9.6 million cancer deaths in 2018. Aims: The aim of this study is to describe for the first time prevalence (PP), incidence rate (Ir), and reported mortality for patients with cancer in Isfahan Province/Iran. Materials and Methods: The study was conducted in Isfahan Kidney Transplantation Research Center. Information related to the surveillance and epidemiology were collected from the Isfahan Cancer Registry (2011-2015). The cancer sites studied were defined according to the international classification of diseases for oncology (Third Edition). PP and Irs were calculated and expressed per 100,000 persons. Statistical Analysis Used: The statistical analyses of dBase was performed using Microsoft Excel and SPSS version 20 (Chicago, IL, USA) for windows. Results: In all, there were 30,465 cancer cases that were comprised 22,282 alive and 8183 deceased reported individuals. For the total population, the PP was calculated as 611.5 and Irs significantly increased (P < 0.05) from 137.5–167.4. The mean (standard deviation, Min-Max) age of the patients was 59.3 (17.5, 1–110) years. The PP were ranked as breast (179.8), digestive system (145.6), and genital system (123.2), skin (77.1), urinary system (42.5), respiratory system (39.1), endocrine system (33.7), leukemia (32.2), brain and other nervous system (20.9), lymphoma (11.4) oral cavity and pharynx (8.2), heart (5.7), bones and joints (5.2), and eye-orbit (1.3). Conclusions: There was a 21.8% increase in the Irs over the study period. The PP associated with the digestive system was highest in both genders. In relation to age, cancers occurred in 67% associated with active years of life. Therefore, for the allocation of health-care resources, attention toward strategic-based-research associated with pharmacotherapy, and surgical care seem to be valuable.
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