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Data availability regarding gynecological malignancies is essential for policymaking and future planning. No researchers have assessed the prevalence of gynecological cancer in Tabuk, Saudi Arabia. We aimed to assess the same in Tabuk, Saudi Arabia. retrospective study was conducted in King Fahd Specialists Hospital in Tabuk City, KSA, from November 2023 to February 2024. The hospital was randomly chosen from the four central hospitals in Tabuk City. All the records of adult women who were diagnosed with cancer in the years 2019-2021 were approached. A data sheet was used to gather the age, type of cancer, method of diagnosis, and laterality. The Statistical Package for Social Sciences was used for data analysis. Out of 544 patients with malignancies, the most common cancers in Tabuk City were breast, colon, and thyroid (18.2%, 12.7%, and 12.1 respectively), while gynecological malignancies were the seventh of all cancers. Uterine and ovarian tumors were found in 1.7% and 1.5%; all were malignant, and 45% were adenocarcinoma—the diagnosis histology 52.6%, 36.8%, and surgery in 10.6%. The majority of the tumors were bilateral (84.2%), 10.6 involved the right side, and 5.2% involved the left. Gynecological malignancies ranked sixth among cancers in Tabuk City; uterine cancer was the most prevalent gynecological cancer, followed by ovarian cancer, and most cases were adenocarcinoma. The methods of diagnosis were histology and cytology, followed by surgery. Further extensive multicenter studies investigating gynecological malignancy patterns and risk factors are suggested.
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