Effects of Almond Porridge, Grape Extract, and Pea Syrup on Fatigue Severity of Patients with COVID-19

AJA Hospital in Tehran, Iran, will host this randomized, double-blind, placebo-controlled clinical study from March through December 2022. Almond porridge, grape extract, and pea syrup (AGP combination) + routine care and placebo + routine care groups were created at random from patients with COVID-19. During his or her stay in the hospital, the patient had a mixture of almond porridge and grape extract around 10 o'clock that contained 25 grams of almonds and 8 ccs of grape extract. Additionally, during the hospital stay, 30 grams of chickpeas were included in the snack at 16 o'clock. The Fatigue Assessment Scale (FAS) was used to evaluate patients at baseline, discharge, three months, and six months. The 6-month duration of the experiment was successfully completed by 75 patients in the AGP group and 71 individuals in the placebo group. Baseline and discharge FAS scores were used to compare patients in the two experimental groups. At the month 3 (p<0.001) and month 6 (p<0.001) visits, the AGP group, however, had a substantially lower FAS score. From baseline through months 3 and 6, the FAS score in the AGP considerably decreased (p <0.001) and declined (p <0.001) more than in the placebo group. Repeated measures analysis confirmed this and found a significant time-x-treatment interaction impact for AGP on the FAS score (F=13.029; η_p²=0.083; P<0.001). Finally, results revealed that after discharge, patients in the AGP group had significantly decreased C-reactive protein (CRP) levels (p = 0.021).