Clear cell adenocarcinoma of uterine cervix in a 19-year-old virgin unrelated to diethylstilbestrol exposure

Clear-cell carcinoma of cervix (CCC) is rarely seen in clinical practice nowadays, especially post the diethylstilbestrol (DES) era. Its association is well established with DES exposure in the adolescent age group. We report a rare case of CCC in a 19-year-old Asian female with no history of exposure to DES. She underwent radical hysterectomy with unilateral salpingoopherectomy and was kept on follow-up and had shown no signs of recurrence even after 1 year of follow-up. Relevant literature is reviewed including possible etiology, appropriate treatment, and prognostic factors.