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The objective of this research is to examine the connection between mental health disorders and psychological well-being in cancer patients who have been diagnosed with COVID-19 and are receiving treatment at Ali Ibn Abi Talib (AS) Hospital in Zahedan city. This study is descriptive and correlational. The target population for this research includes all cancer patients who were hospitalized with a COVID-19 diagnosis at Ali Ibn Abi Talib (AS) Zahedan Hospital in the year 1400. A sample of 127 individuals was selected from the target population using an available sampling method. The overall mean score for psychological well-being in cancer patients is 35.06, with a standard deviation of 7.74. Based on the normalized mean score of the questionnaire, this indicates a moderate to low level of psychological well-being among the participants. The overall mean score for psychological disorders in cancer patients is 200.58, with a standard deviation of 51.12. According to the questionnaire's norms, this suggests a high level of psychological disorders among the participating cancer patients. Among the subscales of psychological disorders, psychotic disorder shows the strongest negative and significant correlation with psychological well-being at a significance level of 0.01. Additionally, phobia, second to psychosis, demonstrates a negative and significant correlation with psychological well-being at a significance level of 0.01. No significant relationship was found between aggression and psychological well-being in cancer patients. Psychological disorders in cancer patients with a COVID-19 diagnosis have a substantial impact on the treatment process, as well as the vulnerability and severity of the disease.
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