Hepatitis C is a viral infection that causes liver cirrhosis and cancer in chronic instances. Blood and blood products are one of the most common routes for the illness to spread. Patients who get HCV through blood transfusions are patients who require frequent blood transfusions and blood products. As a result, the present study aims to investigate the incidence of the hepatitis C virus in major thalassemia patients and hemodialysis patients in Yasuj. After documenting personal information like as age, sex, education, marital status, and blood type, blood samples were obtained from 91 patients with thalassemia major and 40 hemodialysis patients sent to Shahid Beheshti Hospital in Yasouj. Following serum isolation, serum samples were analyzed using an ELISA kit to see if they were infected with the hepatitis C virus. Four individuals with thalassemia major were positive for HCV ELISA and were between the ages of 30 and 40. Hemodialysis patients did not have any positive instances. The majority of thalassemia major patients were self-employed. Three of the four hepatitis C patients (75%) were blood type O. Furthermore; these four individuals were all single. One HCV-positive person was illiterate, one had a high school diploma, and two had a bachelor's degree in terms of education. The findings show that there is no latent hepatitis C in hemodialysis patients in Yasouj and that there are four individuals with thalassemia major who have hepatitis C, which is consistent with previous research.
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