This study aims to examine the effectiveness of preventive strategies on the psychological well-being of hemodialysis patients in Estahban city. The research method is quasi-experimental, including experimental, control, and follow-up groups. The statistical population involved all the patients referred to the hemodialysis department of Imam Khomeini hospital, out of whom 40 people who were poor in terms of mental health and quality of life were randomly selected as a sample and randomly divided into experimental and control groups. Those in the experimental group received interventions in eight sessions, and those in the control group were placed on the waiting list. Using research tools, Reef's (1997) mental health questionnaire, Ware and Sherbourne's 1992 questionnaire on quality of life, and preventive strategies training package was administered to both groups as the pre-test, post-test and three-month follow-up. Descriptive statistics and covariance methods were used at a significance level of 0.05 to analyze the effectiveness of preventive strategies on psychological well-being. The findings of covariance analysis suggested that there is a significant difference between the two groups in psychological well-being and its components (p<0.05). According to the findings, it could be inferred that teaching intervention of preventive strategies in preparation to take care of hemodialysis patients would lead to the enhancement of their psychological well-being.
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