Vitiligo is a skin and autoimmune disease that appears with the appearance of white spots in different sizes and different parts of the skin. This study aimed to determine the effectiveness of compassion-focused therapy on physical health, mental health, and quality of life among patients with vitiligo. The present study was a pre-test-post-test experimental study with a control group and a one-month follow-up. The statistical population included all patients with vitiligo skin disease referred to Razi Dermatology Hospital in 2019, from which 40 participants were selected using the convenience sampling method. The participants were randomly divided into two groups and responded to SF-36 and WHOQOL in three phases namely pre-test, post-test, and follow up phase. The experimental group participated in 8 two-hour group sessions focused on compassion therapy based on the Gilbert therapy package, but the control group did not receive any intervention until the end of the follow-up phase. The results of the analysis of covariance indicated that compassion-focused therapy can increase the physical health, mental health, and quality of life of patients with vitiligo as a treatment. Compassion-focused therapy can be used to increase the physical health, psychological health, and quality of life of patients with vitiligo.
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