Synovial sarcomas are aggressive malignant soft-tissue tumors that often involve large joints of the lower extremities. Cricopharynx is a rare site for primary synovial sarcoma with no case reported until date. We report a case of a 45-year-old male presented with progressive dysphagia and hoarseness of voice. On examination by computed tomography revealed a soft-tissue mass in the cricopharyngeal region with involvement of posterior wall of the laryngeal framework. The endoscopic biopsy was suggestive of biphasic synovial sarcoma, which was confirmed by immunohistochemistry. The patient underwent surgery followed by radiotherapy and chemotherapy. Despite multimodality, management patient developed lung metastasis, and survived for 10 months only. There are no available guidelines for treatment of such rare tumors, and each case needs to be reported.
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