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An official publication of the Middle-Eastern Association for Cancer Research
Clinical Cancer Investigation Journal
ISSN Print: 2278-1668, Online: 2278-0513
ARTICLE
Year: 2015   |   Volume: 4   |   Issue: 3   |   Page: 458-461     View issue

Squamous cell carcinoma with osteoclast-like giant cells masquerading as pleomorphic sarcoma: A rare case report


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Abstract

Squamous cell carcinoma (SCC) with osteoclast-like giant cells (OLGCs) is a rare entity known to occur in skin, breast, lung, and pharynx. Only a single case of SCC containing OLGC in larynx has been reported so far. We report a case of a 65-year-old male patient presenting with sudden onset respiratory distress, who was subjected to biopsy, which was reported as undifferentiated sarcoma which was endorsed on laryngectomy specimen, however, sections from cervical lymph nodes revealed deposits of SCC. Extensive resectioning revealed a single focus showing origin of poorly differentiated carcinoma from the overlying squamous epithelium. Hence in undifferentiated pleomorphic sarcoma, a thorough sectioning and careful search for SCC including immunohistochemical markers should be done to exclude the possibility of a poorly differentiated epithelial malignancy.

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Vancouver
Dewan K, Madan R, Agrawal A, Yadav SPS. Squamous cell carcinoma with osteoclast-like giant cells masquerading as pleomorphic sarcoma: A rare case report. Clin Cancer Investig J. 2015;4(3):458-61. https://doi.org/10.4103/2278-0513.148945
APA
Dewan, K., Madan, R., Agrawal, A., & Yadav, S. P. S. (2015). Squamous cell carcinoma with osteoclast-like giant cells masquerading as pleomorphic sarcoma: A rare case report. Clinical Cancer Investigation Journal, 4(3), 458-461. https://doi.org/10.4103/2278-0513.148945

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ISSN Print: 2278-1668, Online: 2278-0513