Solid - Pseudopapillary tumor of pancreas in an elderly female: Case report of a challenging, rare entity

Solid-Pseudopapillary tumor is a rare pancreatic neoplasm with uncertain to low malignant potential. This rare neoplasm with many pseudonyms occurs predominantly in young woman under the age of thirty years. We present a rare case of Solid-Pseudopapillary tumor of pancreas in an elderly female. The tumor was located in the tail of pancreas; clinically and radiologically diagnosed as Mucinous cystadenocarcinoma. Preoperative CT guided FNA revealed numerous papillary tissue fragments with slender branching fibrovascular cores lined by several layers of uniform tumor cells with round to oval eccentrically placed bland nucleus and abundant light basophilic, finely vacuolated cytoplasm. Occasional tumor cells showed longitudinal nuclear grooves and intracytoplasmic hyaline inclusions. Some of the papillary fragments showed mucinous change in their stalks. Cytological features were suggestive of Solid-Pseudopapillary tumor of pancreas. Histopathological examination of resected specimen confirmed the diagnosis.