Risk of ovarian and cervical cancer in women with positive cancer family history: Results of tabari cohort study

Aim and Background: Positive association between cancer family history and cervical/ovarian cancer could be due to genetic susceptibility or shared environment. The aim of the present study was to identify the association between positive cancer family history and risk of ovarian and cervical cancer. Materials and Methods: In the present case–control study, we have utilized the data collected in the enrollment phase of population-based Tabari cohort study. The case group consisted of participants with ovarian and cervical cancer (17 and 39 individuals, respectively) were selected by the census method. Participants in control groups were matched by age and were selected randomly from the study population. Participants in the control group were twice as participants with cervical cancer and three times as participants with ovarian cancer. Results: There was no association between ovarian cancer family history and other kinds of cancer family history with ovarian cancer (P value: 1.000, 0.146, respectively). Our finding showed no association between cervical cancer family history as well as other kinds of cancer family history with ovarian cancer ovarian (P value: 0.439 and 0.713, respectively). Conclusions: The findings of the present study showed that there is no significant association between cancer family history with ovarian cancer as well as cervical cancer. Among our selected variables, menopause and residency were significantly associated with ovarian and cervical cancer.