Noncaseating epithelioid granuloma, also designated as sarcoid-like granuloma, has been described in association with malignancies. These granulomas are rare in carcinoma, more so when associated with renal cell carcinoma. Here, we describe an association between clear cell renal cell carcinoma and noncaseating granulomas in a 50-year-old female. We also discuss the differential diagnosis that should be considered before establishing such diagnosis, which might have therapeutic and prognostic implications.
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