Regenerative Medicine with iPSC Cells: Generation, Application, and Ethical Issues

Despite medical advances, many diseases still exist without suitable treatments worldwide. Incurable disorders are treated through techniques that decrease bodily and psychological symptoms. Management rather than treatment is the approach physicians take in such circumstances. Researchers are developing new treatment methods to control symptoms and treat diseases without a cure. In modern science, regenerative medicine is a promising treatment option for illnesses that are currently untreatable. In regenerative medicine, there is a new and promising approach to treating patients whose illness has limited or no other treatment options.  Regenerative medicine considers induced pluripotent stem cells (iPSCs) a valuable resource for replacing diseased or damaged tissues since they can be made from any healthy human or patient. Further, reprogramming technology has enabled the study of cell fate decisions as well as the modeling of human diseases, significantly increasing the chances of (i) discovering new drugs through screening formats as well as (ii) treating life-threatening diseases with cell therapy. This review aims to familiarize the reader with the application of iPSCs in different fields of medicine. Due to promising in vivo, in vitro, and pre-clinical findings, many studies have been conducted using these stem cells to treat various conditions. This review aims to familiarize the reader with the application of iPSCs in different fields of medicine.