Primary rhabdomyosarcoma of the fallopian tube: A very rare case

Sarcomas of the fallopian tube are extremely rare malignancies, primary rhabdomyosarcoma (RMS) of the fallopian tube being exceedingly rare entity. We present here a case of primary RMS of the fallopian tube in a 72-year-old female who presented with occasional intermittent colicky abdominal pain and watery per vaginal discharge for 1.5 months. Macroscopic examination of the operated specimen of uterus and ovaries showed that the ampullary end of the right fallopian tube had a 9 cm tumor in its greatest axis. Microscopic examination revealed pleomorphic sarcoma of the right fallopian tube. Immunohistochemical examination revealed the tumor cells expressed desmin, myogenin, and smooth muscle actin (SMA); and are immunonegative for cytokeratin, epithelial membrane antigen (EMA), human melanoma black (HMB)-45, S-100 protein, and h-caldesmon; which was in favor of pleomorphic sarcoma, RMS. Considering the age, performance status of the patient and histology (RMS), adjuvant chemotherapy with single agent doxorubicin was considered.