Pathogenicity Islands in Pathogenic Bacteria and Its Role in Severity and Survival in Diseases

Research on the pathogenicity origin has always been and researchers. It was first performed on human and animal, and plant pathogens. Laboratory samples such as Escherichia coli Spp or the SacB gene in Bacillus subtilis and statistical analyses were extensively used for pathogenicity studies. Pathogenicity islands are large genomic regions. They code toxins and proteins and are affected by pathogenic factors that cause disease in the host. Pathogenic factors are coded by PAIs that have genes with high mutation frequency and the capability to transfer from one tRNA site to another. These studies showed that genetic changes occur in animals and plants in addition to humans. Genome evolution is the process in which the genetic information of strains changes during the time. The present study was conducted to examine the pathogenicity island phenomenon scientifically and identify the factors affecting this phenomenon and the diseases caused by it.