Submit Your Article CMED MEACR meeting
An official publication of the Middle-Eastern Association for Cancer Research
Clinical Cancer Investigation Journal
JCR Impact Factor: 0.1
ARTICLE
Year: 2013   |   Volume: 2   |   Issue: 4   |   Page: 339-343     View issue

Papillary thyroid carcinoma, a diagnostic approach in fine needle aspiration: Review of literature


Shirish Chandanwale, Harsh Kumar, Archana Buch, Shruti Vimal, Pinky Soraisham
Abstract

Background: Despite well-defined cytology features of papillary thyroid carcinoma (PTC) in fine needle aspiration (FNA), diagnostic difficulties do exist while making decision in respect to papillary thyroid carcinoma (PTC) cases. Aims: The aim of this study is to clarify diagnostic significance of various cytology features of PTC and to identify possible diagnostic pitfalls. Materials and Methods: FNA cytology (FNAC) features and clinical findings of 17 PTC cases diagnosed on histology were retrieved. A retrospective review of these cases was performed. Results: The frequency and number of papillary formations, intranuclear cytoplasmic inclusions (INCI), and nuclear grooves (NG) was more in PTC cases as compared to suggestive/suspicious of (S/O) and rule out (R/O) PTC cases. Cyst macrophages forming clusters were seen in six cases. Multinucleated giant cells (MGC) were seen in seven cases. Large MGC with dense cytoplasm and more nuclei were seen in four PTC and one S/O PTC cases. Conclusion: FNAC features of PTC in FNA smears are neither constant nor specific. All the cytology features of PTC should be reported in proper context which allows endocrine specialist to treat and urgent histological verification.

Cite this article
Vancouver
Chandanwale S, Kumar H, Buch A, Vimal S, Soraisham P. Papillary thyroid carcinoma, a diagnostic approach in fine needle aspiration: Review of literature. Clin Cancer Investig J. 2013;2(4):339-43. https://doi.org/10.4103/2278-0513.121536
APA
Chandanwale, S., Kumar, H., Buch, A., Vimal, S., & Soraisham, P. (2013). Papillary thyroid carcinoma, a diagnostic approach in fine needle aspiration: Review of literature. Clinical Cancer Investigation Journal, 2(4), 339-343. https://doi.org/10.4103/2278-0513.121536

Sitemap | What's New | Feedback | Copyright and Disclaimer | Privacy Notice
© Clinical Cancer Investigation Journal | Published by Polaris Publication
Online since 01 December, 2011
Editorial and Ethics Policies
Creative Commons  Open Access Journal View mobile site 
ISSN: Print -2278-1668, Online - 2278-0513