Background: The rapidly fatal cancer that called pancreatic cancer (PC) is the seventh primary source of cancer connected deaths globally. Its treatment is a big challenge with a relatively poor survival even after surgery. The aim of this study was to provide information associated with the PC prevalence, period prevalence (PP), and incidence rates (Irs) in Isfahan Province/Iran. Materials and Methods: Data from March 24, 2011 to March 19, 2015 were obtained from the Isfahan Cancer Registry. Irs and PP were calculated and expressed per 100,000 males. Statistical Analysis Used: The statistical analyses of d-Base were performed using Microsoft Excel and SPSS v. 20 (Chicago, IL, USA) for windows. Results: In all, there were 486 patients with PC. For the total population, the PP was calculated as 9.8 and Irs increased from 2.2 to 2.7/100,000 persons. The mean (standard deviation, min-max) age of the patients was 65.7 (13.0, 12–94) years. The total population was comprised of 150 alive and 336 deceased reported individuals. Conclusions: There was a 22.7% increase in the Irs over the study period. The PP was 58.9% higher in males than females. In 82%, PC occurred at the age between 40 and 80 years. Therefore, for the principal control of the disease, further consideration concerning etiology, pharmacotherapy, and recognizing all relevant features of the PC is crucial.
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