Osteosarcoma (OS) is a primary malignant bone tumor producing osteoid or bone. It occurs less frequently in the jaws and in maxilla occurrence is rare. Jaws are less affected compared to long bones (4-13%). The mean age of occurrence is third to fourth decade. The histopathologic features of OS are highly variable. Herein, we report a rare case of a 72 year old female patient with a swelling in right posterior maxilla, whose clinical, radiographic findings were non-specific, An initial incisional biopsy confirmed neurofibroma. Later, a wide surgical excision was done as there was a spontaneous exacerbation of the growth, and histopathology report came as chondroblastic osteosarcoma.
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