Myeloid sarcoma de novo presenting as generalized lymphadenopathy

Myeloid sarcoma manifesting as multiple lymphadenopathy is a rare entity. Bilateralism is even rarer. It can mimic lymphoma cytologically and histologically. We present a case of myeloid sarcoma mimicking as lymphoma in a 32-year-old male. The patient presented with bilateral neck masses and generalized lymphadenopathy for the past one month. A clinical diagnosis of lymphoma was made but fine needle aspiration cytology, histopathology of excised lymph node, immunophenotyping and cytochemistry on the FNA smears confirmed it to be a myeloid sarcoma and not lymphoma.