Occurrence of bilateral breast neoplasms with same or different histology is rare. It can occur as synchronous (diagnosed within 3 months) or metachronous (separate occurrences) lesions. Breast sarcomas are the most unusual of all breast malignancies. Here, we have reported a case of a 50-year-old postmenopausal lady with metachronous presentation of breast neoplasms of different histology. Right breast ductal carcinoma (stage 3c), followed by left breast sarcoma (size 45 × 34 cm) diagnosed at an interval of 6 years. Modified radical mastectomy was done for both breasts, followed by adjuvant therapy.
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