This study aimed to determine the mediating role of family flexibility in the relation of emotion regulation and psychological cohesion to the psychological resilience of adolescents. The research method was descriptive correlation and path analysis. The statistical population was all adolescents aged 15-18 years in Isfahan. The research sample was 299 people. The data were collected through Garnfsky et al.'s (2011) Cognitive Emotion Regulation Questionnaire, Antonowski's (1987) Cohesion Sense Questionnaire, Shakeri Family Flexibility Scale (2003), and Connor-Davidson Resilience Questionnaire (2003). Data analysis was performed with descriptive and path analysis using SPSS-25 and Amos-24 software. The results showed that the proposed model has a goodness of fit. Emotion regulation, psychological cohesion, and family Resilience have a positive and significant relationship with psychological resilience (p<0.01). The direct paths of cognitive emotion regulation, psychological cohesion, and family flexibility to psychological resilience were significant (p<0.01). The indirect paths of cognitive Emotion Regulation and Psychological Cohesion to psychological resilience were significant with the mediation of family flexibility (p<0.01). Based on the results of the present study, we must pay attention to the mediating role of family flexibility in the relation of emotion regulation and psychological cohesion to psychological resilience as a suggestion and that therapists should include this component in their therapeutic application.
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