Low-grade adenosquamous carcinoma breast in 55-years-old female: A diagnostic challenge

Low-grade adenosquamous (LGAS) carcinoma is rare morphological variant of metaplastic breast carcinoma. Only few cases have been reported in the literature so far. We reported a case of LGAS carcinoma in 55-years-old female who presented with huge lump breast since 6 months. On fine needle aspiration cytology, it was diagnosed as mesenchymal tumor with uncertain malignant potential. Mastectomy without axillary clearance was performed. On histopathology diagnosis of LGAS carcinoma was made and patient was kept on regular follow-up. Due to limited literature available LGAS carcinomas are usually misdiagnosed and treated as benign breast lesions. These tumors have risk of local recurrence after incomplete excision and low metastatic potential also. So, high index of suspicion should always be kept for these tumors to diagnose them at early stage.