The most common intraocular malignancy in adults is metastases from a systemic malignancy. The choroid is the most common site followed by iris and ciliary body; other sites being orbit, eyelids, lacrimal glands, extraocular muscles, and bulbar conjunctiva. However, iris metastases from renal cell carcinoma (RCC) have been reported sparsely in the literature. The present case report describes the unique morphology of iris metastases thought initially to be a benign iris cyst which later proved to be secondary metastases from RCC. This article also describes briefly the review of the relevant literature and the management protocol in such patients.
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