Investigating the Effect of Lead Poisoning on All Related Organs Biochemically

Lead is considered one of the most significant poisons and poisonings in farm animals. Young cows, sheep, and horses are affected by this poisoning. However, their sensitivity is lesser than cows. The present study investigates the effect of lead poisoning on all related organs biochemically.

In the present study, fourteen New Zealand white male rabbits were divided into experimental (N=7) and control g (N=7) groups. They were kept in metal cages with the same food and water and the laboratory conditions with an average weight of 2700 gr to 3500 gr. The experimental group was injected with 6.5 mg/kg of lead acetate and 3 ml of distilled water intraperitoneally every other day for 7 weeks. The control group was injected with physiological serum every other day for 7 weeks intraperitoneally. Subsequently, the biochemical parameters of ALT, AST, glucose, creatine, and urea enzymes were determined by the photometric method.

In the experimental group, there is no protective response in the eyes, and the rabbits have movement disorders and were pale. Also, the biochemical results of the study showed a significant difference between the experimental group and the control group in terms of aspartate aminotransferase (P<0.05).