Hyoscine and Lidocaine-Prilocaine Cream for Prevention of Postoperative Catheter-Related Bladder Discomfort: A Prospective Randomized Trial

Catheter-related bladder discomfort is an uncomfortable complication for patients undergoing urinary catheter placement during surgery. Hyoscine and lidocaine-prilocaine cream affect catheter-related bladder discomfort, but it is not clear which is more effective. This study aimed to evaluate the effects of two drugs on the prevention of catheter-related bladder discomfort. In this triple-blinded prospective randomized clinical trial, 105 patients undergoing non-urological surgery that required intraoperative urinary catheterization were selected by convenience sampling and divided into three groups using random methods. The hyoscine group (n=35) received 20 mg of intravenous hyoscine immediately before the end of anesthesia. The catheter was dipped in 3 g lidocaine-prilocaine cream for catheterization in the lidocaine-prilocaine group (n = 35). Routine interventions were performed in the control (lidocaine) group (n = 35). The catheter was dipped in 3 g lidocaine cream for catheterization in the hyoscine and control groups. The incidence and severity of catheter-related bladder discomfort were assessed one, two, three, and four hours after the end of anesthesia. In the first hour after anesthesia, the incidence of catheter-related bladder discomfort in the hyoscine group was lower than that in the other groups (p=0.028), but 2, 3, and 4 h after anesthesia didn’t differ (p>0.05). The severity of catheter-related bladder discomfort wasn’t significantly different among the three groups (p<0.05). According to the results, intravenous hyoscine is more effective than lidocaine and lidocaine-prilocaine creams in preventing catheter-related bladder discomfort. Therefore, this drug could be used for preventing catheter-related bladder discomfort.