Ewing′s sarcoma humerus presenting along with metastatic breast nodule: An unusual case report

Ewing′s sarcoma is a highly malignant primary bone tumor and most frequently observed in children and adolescents but rare in adults. Usual sites of metastasis are lung, pleura, other bones and occasionally to lymph node, central nervous system, and liver. Metastasis into breast is extremely rare and only one case has been reported. Most common tumors metastasizing into breast are lymphoma, malignant melanoma, and rhabdomyosarcoma. A 25-year-old female presented simultaneously with both left arm swelling and breast lump. Fine needle aspiration done from both swellings revealed similar morphology and comprised monomorphic population of round cells dispersed singly with scant cytoplasm and reticulogranular chromatin. IHC done on cell block material was positive for CD99. Hence diagnosis of Ewing′s sarcoma metastasizing to breast was made. Hereby, we present a rare case of Ewing′s sarcoma humerus with simultaneous metastatic deposit in breast as the initial presentation.