Neoplastic cells with myoepithelial differentiation are often present in both benign and malignant salivary gland neoplasms. Potential diagnostic problems may arise due to morphologic heterogeneity of myoepithelial cell-rich lesions in fine-needle aspiration cytology (FNAC). Myoepithelial carcinoma is a malignant salivary gland tumor composed exclusively of cells with myoepithelial differentiation. Histopathologically, it is a well-established entity but its cytological features have rarely been reported. We report a case of myoepithelial carcinoma of minor salivary gland in a 62-year-old female diagnosed preoperatively by FNAC. Awareness of diverse cytoarchitectural patterns and immunohistochemical profile is crucial for accurate identification.
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