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An official publication of the Middle-Eastern Association for Cancer Research
Clinical Cancer Investigation Journal
ISSN Print: 2278-1668, Online: 2278-0513
ARTICLE
Year: 2014   |   Volume: 3   |   Issue: 5   |   Page: 398-400     View issue

Cytodiagnosis of extranodal natural killer/T-cell lymphoma, nasal type: Report of two cases


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Abstract

Extranodal natural killer (NK)/T-cell lymphoma, nasal type (NK/T) is relatively rare, associated with aggressive behavior and poor prognosis. Histopathological findings, immunohistochemical study, and Epstein-Barr virus-encoded ribonucleic acid in situ hybridization are essential for the diagnosis. There are a few case reports in the literature describing the cytological findings of these uncommon lymphomas. We herein describe cytological findings in two cases of extranodal NK/T-cell lymphoma, nasal type presenting as lacrimal gland and/or nasal masses. Fine-needle aspiration smears revealed small to medium-sized lymphoid cells showing irregular nuclear outline, moderate amounts of light basophilic cytoplasm containing fine azurophilic granules in most of the cells. Some of these atypical lymphoid cells showed tongue-like projections of cytoplasm from one or both sides of the cells. Histopathological examination revealed typical angoicentric, angiodestructive growth pattern of these lymphomas.

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Vancouver
Mardi K, Madan S. Cytodiagnosis of extranodal natural killer/T-cell lymphoma, nasal type: Report of two cases. Clin Cancer Investig J. 2014;3(5):398-400. https://doi.org/10.4103/2278-0513.138059
APA
Mardi, K., & Madan, S. (2014). Cytodiagnosis of extranodal natural killer/T-cell lymphoma, nasal type: Report of two cases. Clinical Cancer Investigation Journal, 3(5), 398-400. https://doi.org/10.4103/2278-0513.138059

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ISSN Print: 2278-1668, Online: 2278-0513