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Clinical Cancer Investigation Journal
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Year: 2014   |   Volume: 3   |   Issue: 5   |   Page: 398-400     View issue

Cytodiagnosis of extranodal natural killer/T-cell lymphoma, nasal type: Report of two cases


Kavita Mardi, Siddharth Madan
Abstract

Extranodal natural killer (NK)/T-cell lymphoma, nasal type (NK/T) is relatively rare, associated with aggressive behavior and poor prognosis. Histopathological findings, immunohistochemical study, and Epstein-Barr virus-encoded ribonucleic acid in situ hybridization are essential for the diagnosis. There are a few case reports in the literature describing the cytological findings of these uncommon lymphomas. We herein describe cytological findings in two cases of extranodal NK/T-cell lymphoma, nasal type presenting as lacrimal gland and/or nasal masses. Fine-needle aspiration smears revealed small to medium-sized lymphoid cells showing irregular nuclear outline, moderate amounts of light basophilic cytoplasm containing fine azurophilic granules in most of the cells. Some of these atypical lymphoid cells showed tongue-like projections of cytoplasm from one or both sides of the cells. Histopathological examination revealed typical angoicentric, angiodestructive growth pattern of these lymphomas.

Cite this article
Vancouver
Mardi K, Madan S. Cytodiagnosis of extranodal natural killer/T-cell lymphoma, nasal type: Report of two cases. Clin Cancer Investig J. 2014;3(5):398-400. https://doi.org/10.4103/2278-0513.138059
APA
Mardi, K., & Madan, S. (2014). Cytodiagnosis of extranodal natural killer/T-cell lymphoma, nasal type: Report of two cases. Clinical Cancer Investigation Journal, 3(5), 398-400. https://doi.org/10.4103/2278-0513.138059

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ISSN: Print -2278-1668, Online - 2278-0513