Colitis cystica profunda mimicking adenocarcinoma

Colitis cystica profunda is a rare benign condition of the rectum and colon and is characterized by benign intramural mucous containing glands. It can be easily misdiagnosed as invasive adenocarcinoma clinically as well as on imaging modalities. The definite diagnosis can only be made on histopathology. We present a case of 50-year-old male who came with the complaints of intermittent abdominal pain and abdominal distension.