%0 Journal Article
%T Squash cytology of langerhans cell histiocytosis of sellar region
%A Supriya Verma
%A Parinitha Sangam
%A Ravikala Rao
%J Clinical Cancer Investigation Journal
%@ 2278-0513
%D 2019
%V 8
%N 6
%R 10.4103/ccij.ccij_66_19
%P 257-260
%X 
Langerhans cell histiocytosis (LCH) is a systemic disease, which usually involves the skeleton and skin of children with occasional involvement of the central nervous system (hypothalamo–pituitary axis). We report the case of a 16-year-old male with a space-occupying lesion (SOL) in the sellar region and diabetes insipidus. However, no systemic abnormality was noted. A clinical diagnosis of pituitary adenoma was given. However, on intraoperative consultation by squash smears, cells with nuclear grooves and few eosinophils were seen. Hence, a differential diagnosis of LCH was also given, which was confirmed by histopathology and immunohistochemistry. Hence, as a matter of fact, LCH should be considered as one of the rare differential diagnoses of SOL of sellar region.

%U https://ccij-online.org/article/squash-cytology-of-langerhans-cell-histiocytosis-of-sellar-region-823