TY  - JOUR
T1  - Spindle Cell Squamous Cell Carcinoma of the Tongue: A Rare Variant at an Even Rarer Location
A1  - Banyameen Iqbal
A1  - Akshi Raj
A1  - Sushma Gurwale
A1  - Charusheela Gore
A1  - Madhuri Singh
JF  - Clinical Cancer Investigation Journal
JO  - Clin Cancer Investig J
SN  - 2278-0513
Y1  - 2022
VL  - 11
IS  - 6
DO  - 10.51847/gZnNXP2qlT
SP  - 1
EP  - 3
N2  - Spindle cell carcinoma (SpCC) is an unusual variant of squamous cell carcinoma (S.C.C.) of the head and neck region. It is a rare biphasic neoplasm.  SpCC is an unusual morphological variant of S.C.C.  It is characterized by the presence of both carcinomatous as well as sarcomatous component and accounts for 2 to 3% of all the S.C.C.s. Seven years ago, the W.H.O. classification has placed this tumor under the malignant epithelial tumors and called it SpCC. The histogenesis of spindle cells remains controversial and is believed to be monoclonal epithelial neoplasia with a close association with squamous carcinoma cells. Since SpCC is a rare tumor, its histopathological diagnosis is often very complex. Immunohistochemistry (I.H.C.) supports the epithelial nature of this tumor. Both neoplasia components possess immunoreactivity for cytokeratin and vimentin. We are presenting a case of a middle-aged man who was diagnosed with this rare variant at an even rarer location.
UR  - https://ccij-online.org/article/spindle-cell-squamous-cell-carcinoma-of-the-tongue-a-rare-variant-at-an-even-rarer-location-8aouqax1px8ur2u
ER  -