TY - JOUR T1 - Significance of early detection of oral malignant melanoma: Some reasonable facts A1 - Manish Gupta A1 - Manas Gupta A1 - Avanti Aggarwal A1 - Ravish Ahuja A1 - Abhishek Pachauri A1 - Prince Kumar JF - Clinical Cancer Investigation Journal JO - Clin Cancer Investig J SN - 2278-0513 Y1 - 2013 VL - 2 IS - 3 DO - 10.4103/2278-0513.119248 SP - 178 EP - 180 N2 - In literal terms, the melanoma is malignant tumors comprising of melanocytes in which cells are derived from the neural crest that basically constitute the melanin pigment in the basal and supra basal layers of the epithelium. The oral malignant melanoma (OMM) is seen with maxillary gingiva of males was previously considered as a fatal disease; however, in recent literature search illustrates the biological nature and behavior of the disease at the molecular levels. Even if these lesions are biologically aggressive, they often go unnoticed since, they are clinically a symptomatic in the early stages and usually present merely as a hyperpigmented patch on the gingival surface. These lesions if diagnosed at a nearly in situ stage are potentially curable and definitely have a better prognosis, but unfortunately as they are clinically asymptomatic, it results in delayed diagnosis thus making the prognosis extremely poor. UR - https://ccij-online.org/article/significance-of-early-detection-of-oral-malignant-melanoma:-some-reasonable-facts-111 ER -