TY  - JOUR
T1  - Role of altered fractionation in radiation therapy with or without chemotherapy in management of carcinoma cervix: Time to revisit in the current COVID-19 pandemic
A1  - Deepak Agrawal
A1  - Neha Agrawal
A1  - Sovan Sarangdhar
A1  - Vinita Kumari
A1  - Narvada Narain
A1  - Neelam Lader
A1  - Sanjog Pal
A1  - Satyajit Pradhan
JF  - Clinical Cancer Investigation Journal
JO  - Clin Cancer Investig J
SN  - 2278-0513
Y1  - 2021
VL  - 10
IS  - 2
DO  - 10.4103/ccij.ccij_155_20
SP  - 53
EP  - 59
N2  - 
Severe acute respiratory syndrome coronavirus 2 as COVID-19 virus has affected the entire world and so to the cancer care and health-care facility. Cancer cervix is one of the common malignancies among women in developing and underdeveloped countries. Various challenges are being faced by patients and health-care providers to deliver optimal treatment under prescribed time frame. Faster delivery of whole treatment is desirable in the current pandemic. Overall treatment time in cancer cervix has prognostic value. Adoption of altered fractionation to delivered external beam radiation therapy could be a method for faster delivery of whole treatment. Altered fractionation such as hyperfractionation (HFX), hypofractionation, and accelerated fraction alone or with HFX has already been experimented for the past three decades. The total duration of treatment has been significantly reduced without addition of much toxicity. Few studies had also highlighted the feasibility of addition of chemotherapy to such fractionation schedule. However, prospective studies are still warranted to generate data to further support its use in the future.

UR  - https://ccij-online.org/article/role-of-altered-fractionation-in-radiation-therapy-with-or-without-chemotherapy-in-management-of-carcinoma-cervix:-time-to-revisit-in-the-current-covid-19-pandemic-889
ER  -