%0 Journal Article %T Rectal adenocarcinoma with extensive choriocarcinomatous differentiation: Report of a rare occurrence %A Kavita Mardi %A Saurabh Gupta %A Neelam Gupta %A Vidisha Mahajan %J Clinical Cancer Investigation Journal %@ 2278-0513 %D 2013 %V 2 %N 1 %R 10.4103/2278-0513.110790 %P 60-62 %X We report a rare case of choriocarcinomatous differentiation of tumor cells in the rectal adenocarcinoma of a 54-year-old female who presented with pain abdomen and passage of bloody stools. CT scan was suggestive of a malignant tumor in the rectum. Histologic examination of the tumor revealed a minor component of moderately differentiated adenocarcinoma that showed extensive trophoblastic differentiation. Positive immunostaining for beta-hCG of tumor cells in these areas confirmed the diagnosis. Since such tumors behave aggressively and confer bad prognosis, they constitute a distinct clinical entity of a gastrointestinal tumor. %U https://ccij-online.org/article/rectal-adenocarcinoma-with-extensive-choriocarcinomatous-differentiation:-report-of-a-rare-occurrence-81