TY - JOUR T1 - Primary osteosarcoma of the breast presented as a large breast abscess A1 - N Nawarathna A1 - N Kumarasinghe A1 - P Ratnayake A1 - R. J. K. Senevirathna JF - Clinical Cancer Investigation Journal JO - Clin Cancer Investig J SN - 2278-0513 Y1 - 2015 VL - 4 IS - 3 DO - 10.4103/2278-0513.154042 SP - 431 EP - 434 N2 - Primary extra osseous osteogenic sarcoma is one of the rarest forms of malignant tumor of the breast. It can arise as a result of osseous metaplasia of a preexisting neoplasm or from a none - phyllodes sarcoma of a previously normal breast. Due to its rarity, natural history and optimal treatment methods remain unclear. A 60-year-old patient presented to the surgical casualty with large breast abscess. Abscess wall histology revealed an osteosarcoma of the breast. Left total mastectomy with axillary clearance was performed. Histology and subsequent immunohistochemical studies confirmed the diagnosis of osteogenic sarcoma without lymph nodal metastasis. The patient was referred to the oncologist for further management. Rare types of breast tumors can be presented as breast abscess. Incision and drainage together with wall biopsy help to exclude associated sinister pathologies. Diagnosis of primary osteosarcoma of the breast was made using histological and immunohistochemical findings once the possible primary from the sternum and ribs were excluded. Treatment is as for sarcomas affecting other locations and should comprise a multidisciplinary approach. UR - https://ccij-online.org/article/primary-osteosarcoma-of-the-breast-presented-as-a-large-breast-abscess-414 ER -