TY - JOUR T1 - Pleural biopsy: A superior procedure than pleural fluid cytology in diagnosing pleural malignancy A1 - Biswajit Biswas A1 - Sudarshan Sharma A1 - Rameshwar Negi A1 - Neelam Gupta A1 - Virender Jaswal A1 - N Niranjan A1 - Balraj Singh JF - Clinical Cancer Investigation Journal JO - Clin Cancer Investig J SN - 2278-0513 Y1 - 2015 VL - 4 IS - 4 DO - 10.4103/2278-0513.158457 SP - 530 EP - 533 N2 - Background: The present study is designed to evaluate the role of pleural fluid cytology and pleural biopsy in diagnosing pleural diseases and to study the advantages and disadvantages of thoracocentasis and pleural biopsy. Materials and Methods: We prospectively included 66 consecutive indoor patients over a duration of 1-year. Pleural fluid was collected, cytological smears were made from the fluid. Plural biopsy was obtained in the same patient by Copeā€²s needle. Adequate pleural biopsy tissue yielding specific diagnosis was obtained in 47 (71.2%) of cases. Results: Tuberculosis was the commonest nonneoplastic lesion followed by chronic nonspecific pleuritis comprising 60% and 33.3% of the nonneoplastic cases respectively and tuberculosis was predominantly diagnosed in younger age group. Majority (70.8%) of malignancy were in the age group of >50-70. Adenocarcinoma was found to be the commonest (66.7%) malignant neoplasm in the pleurae followed by small cell carcinoma (20.8%). Conclusion: Pleural biopsy is a useful and minimally invasive procedure. It is more sensitive and specific than pleural fluid smears. UR - https://ccij-online.org/article/pleural-biopsy:-a-superior-procedure-than-pleural-fluid-cytology-in-diagnosing-pleural-malignancy-442 ER -