TY  - JOUR
T1  - Neoadjuvant chemotherapy in locally advanced cancers of oral cavity
A1  - Ashok Das
A1  - Kaberi Kakati
A1  - Nizara Baishya
A1  - Partha Roy
A1  - Amal Kataki
JF  - Clinical Cancer Investigation Journal
JO  - Clin Cancer Investig J
SN  - 2278-0513
Y1  - 2017
VL  - 6
IS  - 1
DO  - 10.4103/ccij.ccij_128_16
SP  - 116
EP  - 118
N2  - 
Oral cancers constitute a major burden of cancer in northeastern part of India. This can be attributed to the increased consumption of tobacco in various forms such as chewing, snuffing, powder or paste and smoking along with betel nut and areca nut. The majority of patients with oral cavity cancer present in an advanced stage which carries a poor prognosis. We present here a case of locally advanced (T4b) oral cavity cancer where 5-fluorouracil (5FU) and methotrexate (MTX) were used as neoadjuvant chemotherapy to attain a surgically resectable stage. The objective of this case report is to show the efficacy and impact of 5FU and MTX as induction chemotherapy in advanced oral cancers.

UR  - https://ccij-online.org/article/neoadjuvant-chemotherapy-in-locally-advanced-cancers-of-oral-cavity-669
ER  -