TY - JOUR T1 - Malignancy in pilonidal disease: Uncommon occurrence A1 - Snigdha Goyal A1 - Sunder Goyal A1 - Monika Garg JF - Clinical Cancer Investigation Journal JO - Clin Cancer Investig J SN - 2278-0513 Y1 - 2013 VL - 2 IS - 2 DO - 10.4103/2278-0513.113640 SP - 153 EP - 155 N2 - Development of malignancy in pilonidal sinus is a rare complication. The disease occurs most frequently in men. About 69 cases have been reported so far in literature. The lesion is mostly a well-differentiated squamous cell carcinoma. Best treatment is local wide excisions along with a short period of local wound care. After healthy granulation tissue, definitive closure of the defect is done with rotational flaps or skin grafts. Fine needle aspiration cytology is mandatory for palpable inguinal nodes. The prognosis is very poor if inguinal node has metastatic deposits. Radiation therapy may be used as palliative therapy for local bone or soft tissue recurrences. Recently, both topical and systemic chemotherapy have been used without promising results. UR - https://ccij-online.org/article/malignancy-in-pilonidal-disease:-uncommon-occurrence-103 ER -