TY - JOUR T1 - Helical tomotherapy based intensity modulated radiotherapy for the management of difficult clinical situations in breast cancer A1 - Animesh Saha A1 - Anurupa Mahata A1 - Rajkumar Shrimali A1 - Rimpa Achari A1 - Indranil Mallick A1 - Sanjoy Chatterjee JF - Clinical Cancer Investigation Journal JO - Clin Cancer Investig J SN - 2278-0513 Y1 - 2015 VL - 4 IS - 4 DO - 10.4103/2278-0513.159788 SP - 543 EP - 547 N2 - Helical tomotherapy (HT) can achieve a homogenous dose distribution in the planning target volume while minimizing the dose to the organ at risk. Tomotherapy has been used for complex breast cancer radiotherapy including bilateral breast irradiation, pectus excavatum, and internal mammary chain (IMC) nodal irradiation. This report details our experience of using HT in breast cancers in newer clinical indications. Three patients with SCF nodal involvement (case 1), high level III axillary node recurrence (case 2), and composite irradiation of SCF, IMC, and whole breast (case 3) were treated using brachial plexus sparing HT. It was possible to boost the SCF, reirradiate the high level III axillary nodal recurrence and treat complex volume of breast, SCF, and IMC with acceptable and safe dose volume histogram constraints and with good homogeneity and conformity indices. The treatment was successful in controlling disease locoregionally at a 15 months follow-up. No patients reported symptoms suggestive of brachial plexopathy UR - https://ccij-online.org/article/helical-tomotherapy-based-intensity-modulated-radiotherapy-for-the-management-of-difficult-clinical-situations-in-breast-cancer-446 ER -