TY  - JOUR
T1  - Fasting inhibits human cancer progression via the epithelial-mesenchymal transition process: Important evidence unraveled
A1  - Ala-Eddin Al Moustafa
JF  - Clinical Cancer Investigation Journal
JO  - Clin Cancer Investig J
SN  - 2278-0513
Y1  - 2012
VL  - 1
IS  - 4
SP  - 181
EP  - 183
N2  - Metastatic cancer disease is responsible for the majority of cancer-related deaths in human cancer patients. In parallel, recently it was pointed-out that fasting could play an important role during cancer treatment and progression via the deregulation of insulin-like growth factor-1 (IGF-1) as well as others growth factors and genes. Meanwhile, it is established that the epithelial-mesenchymal transition (EMT) is a major process for the progression of cancer cells from non-invasive to invasive form. We believe that fasting can inhibit cancer progression and metastasis though the reduction of IGF-1 level and consequently the inhibition of EMT; in this paper, we present some evidence to confirm this association.
UR  - https://ccij-online.org/article/fasting-inhibits-human-cancer-progression-via-the-epithelial-mesenchymal-transition-process:-important-evidence-unraveled-49
ER  -