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The purpose of the present study was to evaluate the effect of eight weeks of moderate-intensity intermittent and resistance exercise on TNF-α in individuals with type 2 diabetes. Thirty diabetic women (51.9 09 5.09 years) were randomly divided into three groups (10 people) resistance training, periodic aerobic training, and control. Periodic aerobic exercise with an intensity of 50-75% MHR and resistance exercise with an intensity of 30-75% 1RM was performed for eight weeks and three sessions per week. ELISA measured IL-33. Data were analyzed using paired t-test and one-way ANOVA at the significance level (p≥0.00.05). (Resistance and intermittent aerobic) exercise reduces TNF-α levels. One of the possible reasons for the increase in serum CTRP-12 in the subjects of the present study is a significant decrease in inflammatory factor TNF-a. The results showed that eight weeks of intermittent resistance and aerobic training could significantly increase the serum levels of IL-33 in diabetic women. This increase was greater in the group of resistance training. In the intergroup study, the changes and increases in IL-33 in the resistance training group were much greater than in the periodic aerobic training group and the control group. These differences were also significant.
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