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An official publication of the Middle-Eastern Association for Cancer Research
Clinical Cancer Investigation Journal
ISSN Print: 2278-1668, Online: 2278-0513
Year: 2022   |   Volume: 11   |   Issue: 1 S   |   Paper ID: CCLS220113

Effect of Eight Weeks of Periodic and Resistant Sports Activities with Moderate Severity on TNF-α and IL33 Body Composition Indices in People with Type 2 Diabetes


The purpose of the present study was to evaluate the effect of eight weeks of moderate-intensity intermittent and resistance exercise on TNF-α in individuals with type 2 diabetes. Thirty diabetic women (51.9 09 5.09 years) were randomly divided into three groups (10 people) resistance training, periodic aerobic training, and control. Periodic aerobic exercise with an intensity of 50-75% MHR and resistance exercise with an intensity of 30-75% 1RM was performed for eight weeks and three sessions per week. ELISA measured IL-33. Data were analyzed using paired t-test and one-way ANOVA at the significance level (p0.00.05). (Resistance and intermittent aerobic) exercise reduces TNF-α levels. One of the possible reasons for the increase in serum CTRP-12 in the subjects of the present study is a significant decrease in inflammatory factor TNF-a. The results showed that eight weeks of intermittent resistance and aerobic training could significantly increase the serum levels of IL-33 in diabetic women. This increase was greater in the group of resistance training. In the intergroup study, the changes and increases in IL-33 in the resistance training group were much greater than in the periodic aerobic training group and the control group. These differences were also significant.

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ISSN Print: 2278-1668, Online: 2278-0513