%0 Journal Article
%T Cytodiagnosis of extragonadal pure yolk sac tumor of sacrococcygeal region
%A Kavita Mardi
%A Neha Bakshi
%J Clinical Cancer Investigation Journal
%@ 2278-0513
%D 2014
%V 3
%N 1
%R 10.4103/2278-0513.125814
%P 105-107
%X Yolk sac tumors (YST) are rare in extragonadal location. Cytologic diagnosis of YST in such instances may be a challenge to the pathologist. We studied Fine needle Aspiration (FNA) material from a sacrococcygeal mass in a 18-month-old female child presenting with a progressively increasing sacrococcygeal mass. Cytologic features include large pleomorphic balls of tumor cells with high nuclear to cytoplasmic ratios, papillary or micro-glandular pattern of growth, cytoplasmic and intra-nuclear vacuoles, and prominent nucleoli. Per Iodic Acid Schiff (PAS) positive intra-cytoplasmic as well as extracellular hyaline globules were also seen. The subsequent biopsy was consistent with the FNA diagnosis, and immuno-histochemically, the tumor cells were positive for Alpha Feto Protein (AFP) supporting the diagnosis.
%U https://ccij-online.org/article/cytodiagnosis-of-extragonadal-pure-yolk-sac-tumor-of-sacrococcygeal-region-160