%0 Journal Article
%T Comparative efficacy of newer antioxidants spirulina and lycopene for the treatment of oral submucous fibrosis
%A Santosh Patil
%A Suneet Khandelwal
%A Sneha Maheshwari
%J Clinical Cancer Investigation Journal
%@ 2278-0513
%D 2014
%V 3
%N 6
%R 10.4103/2278-0513.142618
%P 482-486
%X Context: Oral submucous fibrosis (OSMF) is a high-risk premalignant condition predominantly seen in the Indian subcontinent. The aim of the present study was to compare the efficacy of spirulina and lycopene in the management of OSMF. Materials and Methods: Sixty-eight subjects with clinico-pathologically diagnosed OSMF were included in the study which was conducted from March, 2013 to July, 2013. They were divided equally in two groups, Group A (spirulina group) and Group B (lycopene group). Group A was administered 500 mg spirulina in two divided doses for 3 months, and Group B was given 8 mg lycopene in two divided doses of 4 mg for 3 months. Evaluation for different clinical parameters was done at regular intervals and data was analyzed using the Student′s paired t-test and Chi-square test. P 
%U https://ccij-online.org/article/comparative-efficacy-of-newer-antioxidants-spirulina-and-lycopene-for-the-treatment-of-oral-submucous-fibrosis-280