TY  - JOUR
T1  - Analysis of bone metastasis in head and neck squamous cell carcinoma: Experience of a regional cancer center
A1  - Akhil Kapoor
A1  - Ashok Kalwar
A1  - Satya Narayan
A1  - Narender Kumar
A1  - Mukesh Singhal
A1  - Harvindra Kumar
JF  - Clinical Cancer Investigation Journal
JO  - Clin Cancer Investig J
SN  - 2278-0513
Y1  - 2015
VL  - 4
IS  - 2
DO  - 10.4103/2278-0513.148916
SP  - 206
EP  - 210
N2  - Background: Bone metastasis is a rare occurrence in head and neck squamous cell carcinoma (HNSCC). This retrospective study was performed to analyze the frequency and patterns of skeletal metastasis in HNSCC. Materials and Methods : We analyzed records of 8326 HNSCC patients attending our oncology outpatient department from January 2000 to December 2013. All statistical calculations were performed using MedCalc software for windows, version 12.5.0 (Osterd, Belgium). Results : Bone metastasis was found in 25 patients (0.3% of total HNSCC patients, nasopharynx excluded). 10 patients (0.66%) of carcinoma tonsil had skeletal metastasis. The patients of younger age groups had higher frequency of bone metastasis; 1.56% patients of age group 20-29 years while 0.26% patients of 60-69 years age group had skeletal metastasis (P < 0.001). However, no patient of >70 years age was found to have bone metastasis. Most common site of metastasis was spine (56%) followed by pelvis (32%). Isolated involvement of a single bony site was present in 64% of the metastatic cases. Conclusion: Bone metastasis though very rare, should be considered for evaluation in patients of HNSCC especially in younger patients.
UR  - https://ccij-online.org/article/analysis-of-bone-metastasis-in-head-and-neck-squamous-cell-carcinoma:-experience-of-a-regional-cancer-center-349
ER  -