TY - JOUR T1 - Advanced Diagnostic Methods for Salivary Glands Diseases: A Narrative Review Study A1 - Malak Mohammed AlOsaimi A1 - Abdulaziz Mohammed AlSubaheen A1 - Taif Saleh Jameel A1 - Rand Abdulrahman AlSalamah A1 - Dalal Naseh AlAnzi A1 - Norah Ameen AlOushan A1 - Fahad Fadhel AlShammari A1 - Cristalle Soman JF - Clinical Cancer Investigation Journal JO - Clin Cancer Investig J SN - 2278-0513 Y1 - 2023 VL - 12 IS - 4 DO - 10.51847/pGptDUNgkQ SP - 19 EP - 26 N2 - Effective diagnosis of salivary gland lesions and tumors requires a comprehensive understanding of the intricate composition of these glands. Salivary glands consist of diverse cell types, including epithelial, mesenchymal, ductal, and myoepithelial cells. The complex cellular architecture poses challenges in accurately diagnosing lesions or tumors. Furthermore, external factors such as infections, viruses, and genetic abnormalities that contribute to alterations can influence salivary gland pathophysiology. Therefore, it is crucial to thoroughly grasp the latest World Health Organization classification of salivary gland neoplasms for precise diagnosis and appropriate management. This study focuses on recent advancements in diagnostic methods to establish a practical approach for identifying salivary gland diseases. The researchers found that the best results were achieved when combining multiple salivary biomarkers. The screening protocol demonstrated high accuracy in diagnosing early oral squamous cell carcinoma by utilizing a combination of salivary biomarkers. In conclusion, the use of salivary biomarkers shows excellent promise in the early diagnosis of oral squamous cell carcinoma. UR - https://ccij-online.org/article/advanced-diagnostic-methods-for-salivary-glands-diseases-a-narrative-review-study-f009nebvwueasat ER -