%0 Journal Article %T Absence of Synergistic Effect of Toluidine Blue and Cytomorphometry in Discriminating Dysplasia in Oral Exfoliative Cytology %A Yashi Shrivastava %A Monal Yuwanati %A Narayanan Ganesh %J Clinical Cancer Investigation Journal %@ 2278-0513 %D 2023 %V 12 %N 1 %R 10.51847/W62uZ2A9O8 %P 27-31 %X Numerous tools and techniques such as vital stain, autofluorescence, exfoliative cytology, histomorphometry, etc. were explored in the detection of dysplasia, but have variable sensitivity and specificity. The present study evaluated the effect of toluidine blue in increasing the accuracy of histomorphometry analysis in detection of the dysplasia in OPMDs on exfoliative cytology. An experimental, observational, cross-sectional research was performed on patients attending dental hospitals and in oral health check-up camps suspected of having OPMDs. Cytology smear was collected using the standard protocol before and after the application of a toluidine blue stain over the lesion. Two pathologists performed the dysplasia grading and histomorphometry analysis. Chi-square and t-tests were carried out (p %U https://ccij-online.org/article/absence-of-synergistic-effect-of-toluidine-blue-and-cytomorphometry-in-discriminating-dysplasia-in-o-ex1ceoyp3dcjjht