TY  - JOUR
T1  - A Very Rare Case of Metastases to the Nasal Cavity from Primary Rectal Adenocarcinoma
A1  - Nishant Lohia
A1  - Harish Sadashiva
A1  - Sankalp Singh
A1  - Samir Agarwal
A1  - Vikas Gupta
A1  - Manoj Prashar
A1  - Gaurav Trivedi
JF  - Clinical Cancer Investigation Journal
JO  - Clin Cancer Investig J
SN  - 2278-0513
Y1  - 2022
VL  - 11
IS  - 4
DO  - 10.51847/gEhiWXwo0s
SP  - 1
EP  - 4
N2  - Nasal cavity as the first site of metastases from colorectal adenocarcinoma without metastases elsewhere is generally unheard of and very rare with only a few cases reported in world literature. The diagnostic dilemma and therapeutic challenge are significant when encountered in clinical practice, especially to differentiate it from a primary nasal pathology. Histopathological examination and immunohistochemistry play an important role. We report an unusual and interesting case of adenocarcinoma rectum with nasal metastases. A 65-year-old male was treated for adenocarcinoma rectum with radiotherapy, surgery and chemotherapy and was disease-free for 9 months post-treatment completion. Subsequently, he presented with nasal bleeding and on evaluation was found to have a nasal mass. Histopathological examination and immunohistochemistry confirmed the mass to be a metastasis from the earlier rectal adenocarcinoma. He received palliative haemostatic radiotherapy for bleeding from the nasal mass and was then treated with 6 cycles of 5-fluorouracil and irinotecan-based palliative chemotherapy. The patient achieved a good level of palliation, had near-complete regression of nasal mass on imaging with no new sites of metastases and hence was placed on regular follow up.
UR  - https://ccij-online.org/article/a-very-rare-case-of-metastases-to-the-nasal-cavity-from-primary-rectal-adenocarcinoma-vg9t9gfewso6zhn
ER  -