%0 Journal Article
%T A rare case of acute myeloid leukemia-M6 in a 2-year-old child with complex karyotype
%A Prakas Mandal
%A Gopal Pandey
%A Manik Mondal
%A Bani Ganguly
%J Clinical Cancer Investigation Journal
%@ 2278-0513
%D 2015
%V 4
%N 6
%R 10.4103/2278-0513.165530
%P 756-758
%X Acute erythroid leukemia is a very rare entity in children. Here is a case of erythroleukemia with complex cytogenetics in a child aged 2 years. On immunophenotyping, CD45 versus side scatter (SSC) demonstrated blast population (29%) with intermediate SSC and moderate CD45 expression. The myeloid nature of blast population was confirmed by moderate expression of cytoplasmic myeloperoxidase, CD117, CD13 and CD33. Another population of cells (28%) with low to intermediate SSC and negative CD45 expression revealed dim expression of CD235a (64%) indicating lysis resistant abnormal erythroid progenitors. Conventional cytogenetic analysis by G-banding revealed complex cytogenetics.
%U https://ccij-online.org/article/a-rare-case-of-acute-myeloid-leukemia-m6-in-a-2-year-old-child-with-complex-karyotype-501